Overview
Novel Regimens
CPTR Initiative
The TB Alliance isn't just developing new TB drugs, but leading a revolution in the way that TB drugs are developed. The organization is using the regimen development paradigm to telescope the time it takes to develop novel, multi-drug treatments. Following a robust pre-clinical program and the establishment of the safety and efficacy of individual drug candidates, promising combinations of drugs are tested together to find the most impactful treatment.
CHANGING THE WAY
WE DEVELOP A NEW TB
DRUG REGIMEN
Since the 1950s, researchers have known that TB treatment must be delivered in multi-drug regimens to prevent the development of drug resistance. Traditionally, when developing a new drug, researchers would replace an existing drug within the regimen or add the new candidate to the existing standard treatment. Each of these trials could last six years or longer, which means that a novel TB regimen could take decades to develop using this model. With more than 9 million new cases of TB each year and growing numbers of people resistant to the current treatment, this is an unacceptably long wait for those suffering.see more video
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